SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05487

Signal sequence   MQQQHLFRLNILCLSLMTALPVYA

Length  24

Organism  Neisseria meningitidis serogroup B

UniProt ID  Q06987,

Motif  1..24



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05487.cif

Structure  SPKB05487.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2804.42234

Aliphatic index  134.1666667

Isoelectric point  8.534796248

Charge (pH=7)   1.026064949

Topological polar surface area  1047.46

Aromaticity  0.083333333

Average rotatable bonds  3.791666667

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  37

X logP energy  -6.02553

Hydropathy 



Literature Information


Title  Antigenic relationships of transferrin-binding proteins from Neisseria meningitidis, N. gonorrhoeae and Haemophilus influenzae: cross-reactivity of antibodies to NH2-terminal peptides.

DOI  10.1111/j.1574-6968.1993.tb06148.x,

Publication Year  1993

PubMed ID  8319886,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.