SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05472

Signal sequence   MHLFIGVSLRPLGHGIP

Length  17

Organism  Gallus gallus (Chicken)

UniProt ID  Q03352,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05472.cif

Structure  SPKB05472.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1844.25104

Aliphatic index  131.7647059

Isoelectric point  10.55350111

Charge (pH=7)   1.17979917

Topological polar surface area  650.83

Aromaticity  0.058823529

Average rotatable bonds  3.294117647

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  23

X logP energy  -2.86883

Hydropathy 



Literature Information


Title  Chicken antithrombin. Isolation, characterization, and comparison with mammalian antithrombins and chicken ovalbumin.

DOI  10.1093/oxfordjournals.jbchem.a133806,

Publication Year  1982

PubMed ID  6920385,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.