SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05467

Signal sequence   MKGLVLSFALVALSALCVYG

Length  20

Organism  Rhinella marina (Cane toad) (Bufo marinus)

UniProt ID  Q01584,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05467.cif

Structure  SPKB05467.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2055.56474

Aliphatic index  156

Isoelectric point  8.522939048

Charge (pH=7)   0.934864135

Topological polar surface area  702.93

Aromaticity  0.1

Average rotatable bonds  3.3

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -2.882

Hydropathy 



Literature Information


Title  Protein synthesis at the blood-brain barrier. The major protein secreted by amphibian choroid plexus is a lipocalin.

DOI  NA,

Publication Year  1992

PubMed ID  1385415,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.