SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05466

Signal sequence   MNSPAIVIIIFSTLTFSEA

Length  19

Organism  Limulus polyphemus (Atlantic horseshoe crab)

UniProt ID  Q01528,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05466.cif

Structure  SPKB05466.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2054.42904

Aliphatic index  128.4210526

Isoelectric point  3.849983241

Charge (pH=7)   -1.000240578

Topological polar surface area  759.87

Aromaticity  0.105263158

Average rotatable bonds  3.368421053

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  28

X logP energy  -5.7256

Hydropathy 



Literature Information


Title  Isolation, cDNA cloning, and characterization of an 18-kDa hemagglutinin and amebocyte aggregation factor from Limulus polyphemus.

DOI  NA,

Publication Year  1992

PubMed ID  1429596,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.