SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05465

Signal sequence   MMSSLCGMPLTYLLTAAVLSLSLTDA

Length  26

Organism  Lymnaea stagnalis (Great pond snail) (Helix stagnalis)

UniProt ID  Q00945,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05465.cif

Structure  SPKB05465.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2703.27794

Aliphatic index  127.6923077

Isoelectric point  3.749971056

Charge (pH=7)   -1.064394347

Topological polar surface area  981.17

Aromaticity  0.038461538

Average rotatable bonds  3.307692308

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  40

X logP energy  -8.582

Hydropathy 



Literature Information


Title  Evolution of the vasopressin/oxytocin superfamily: characterization of a cDNA encoding a vasopressin-related precursor, preproconopressin, from the mollusc Lymnaea stagnalis.

DOI  10.1073/pnas.89.10.4593,

Publication Year  1992

PubMed ID  1584795,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.