SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05463

Signal sequence   MISKILCLSLLVAAVVA

Length  17

Organism  Dermatophagoides farinae (American house dust mite)

UniProt ID  Q00855,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05463.cif

Structure  SPKB05463.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1744.26774

Aliphatic index  206.4705882

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  595.4

Aromaticity  0

Average rotatable bonds  3.411764706

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  23

X logP energy  -1.7441

Hydropathy 



Literature Information


Title  Antigenic and structural analysis of group II allergens (Der f II and Der p II) from house dust mites (Dermatophagoides spp).

DOI  10.1016/0091-6749(89)90447-8,

Publication Year  1989

PubMed ID  2732406,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.