SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05462

Signal sequence   MRIKIFMLVTAVVLLCCSGVATA

Length  23

Organism  Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

UniProt ID  P9WIN9,

Motif  1..23



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05462.cif

Structure  SPKB05462.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2440.12034

Aliphatic index  148.2608696

Isoelectric point  8.828181491

Charge (pH=7)   1.873736522

Topological polar surface area  852.13

Aromaticity  0.043478261

Average rotatable bonds  3.47826087

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  33

X logP energy  -4.63583

Hydropathy 



Literature Information


Title  A family of cross-reacting proteins secreted by Mycobacterium tuberculosis.

DOI  10.1111/j.1365-3083.1992.tb03104.x,

Publication Year  1992

PubMed ID  1502498,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.