SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05461

Signal sequence   MSLRLVSPIKAFADGIVAVAIAVVLMFGLANTPRAVAA

Length  38

Organism  Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

UniProt ID  P9WG65,

Motif  1..38



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05461.cif

Structure  SPKB05461.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3854.71444

Aliphatic index  141.3157895

Isoelectric point  11.47969964

Charge (pH=7)   1.998129127

Topological polar surface area  1413.34

Aromaticity  0.052631579

Average rotatable bonds  3.210526316

Number of hydrogen bond donors  49

Number of hydrogen bond acceptors  49

X logP energy  -9.58846

Hydropathy 



Literature Information


Title  Cloning, expression and significance of MPT53 for identification of secreted proteins of Mycobacterium tuberculosis.

DOI  10.1006/mpat.1998.0267,

Publication Year  1999

PubMed ID  10089161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.