SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05458

Signal sequence   MIIKTLLASVAIMLIATVNA

Length  20

Organism  Lucilia cuprina (Green bottle fly) (Australian sheep blowfly)

UniProt ID  P91745,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05458.cif

Structure  SPKB05458.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2086.66294

Aliphatic index  185.5

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  746.02

Aromaticity  0

Average rotatable bonds  3.5

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  28

X logP energy  -3.4117

Hydropathy 



Literature Information


Title  Characterization of a major peritrophic membrane protein, peritrophin-44, from the larvae of Lucilia cuprina. cDNA and deduced amino acid sequences.

DOI  10.1074/jbc.271.15.8925,

Publication Year  1996

PubMed ID  8621536,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.