SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05449

Signal sequence   MSIFPIVLALLLIGLEETEA

Length  20

Organism  Tityus obscurus (Amazonian scorpion) (Tityus cambridgei)

UniProt ID  P84688,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05449.cif

Structure  SPKB05449.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2172.64824

Aliphatic index  180.5

Isoelectric point  3.472799833

Charge (pH=7)   -2.996690332

Topological polar surface area  759.79

Aromaticity  0.05

Average rotatable bonds  3.55

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  27

X logP energy  -1.225

Hydropathy 



Literature Information


Title  Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

DOI  10.1016/j.jchromb.2003.09.002,

Publication Year  2004

PubMed ID  15025998,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.