SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05440

Signal sequence   MLLFTLCFFADQENGGKALA

Length  20

Organism  Ophiophagus hannah (King cobra) (Naja hannah)

UniProt ID  P83234,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05440.cif

Structure  SPKB05440.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2189.57204

Aliphatic index  93

Isoelectric point  4.184374539

Charge (pH=7)   -1.062063843

Topological polar surface area  823.25

Aromaticity  0.15

Average rotatable bonds  3.6

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  29

X logP energy  -5.4824

Hydropathy 



Literature Information


Title  Ohanin, a novel protein from king cobra venom, induces hypolocomotion and hyperalgesia in mice.

DOI  10.1074/jbc.M414137200,

Publication Year  2005

PubMed ID  15668253,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.