SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05437

Signal sequence   MKSLHTICLLFIFIARGNS

Length  19

Organism  Gloydius brevicaudus siniticus (Chinese mamushi) (Agkistrodon blomhoffii siniticus)

UniProt ID  P82144,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05437.cif

Structure  SPKB05437.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2164.65494

Aliphatic index  128.4210526

Isoelectric point  9.834331048

Charge (pH=7)   2.026620329

Topological polar surface area  807.5

Aromaticity  0.105263158

Average rotatable bonds  3.789473684

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  29

X logP energy  -5.18023

Hydropathy 



Literature Information


Title  Purification and characterization of three distinct types of phospholipase A2 inhibitors from the blood plasma of the Chinese mamushi, Agkistrodon blomhoffii siniticus.

DOI  10.1042/bj3250527,

Publication Year  1997

PubMed ID  9230137,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.