SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05436

Signal sequence   MKSFLFCCLLGTFLAIGMC

Length  19

Organism  Gloydius brevicaudus siniticus (Chinese mamushi) (Agkistrodon blomhoffii siniticus)

UniProt ID  P82143,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05436.cif

Structure  SPKB05436.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2098.68364

Aliphatic index  107.8947368

Isoelectric point  8.045790785

Charge (pH=7)   0.811765118

Topological polar surface area  653.6

Aromaticity  0.157894737

Average rotatable bonds  3.578947368

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  28

X logP energy  -1.8363

Hydropathy 



Literature Information


Title  Purification and characterization of three distinct types of phospholipase A2 inhibitors from the blood plasma of the Chinese mamushi, Agkistrodon blomhoffii siniticus.

DOI  10.1042/bj3250527,

Publication Year  1997

PubMed ID  9230137,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.