SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05432

Signal sequence   MAPQNLGTLCLLLLYLLGAAIA

Length  22

Organism  Canis lupus familiaris (Dog) (Canis familiaris)

UniProt ID  P81999,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05432.cif

Structure  SPKB05432.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2272.83254

Aliphatic index  177.7272727

Isoelectric point  5.919503212

Charge (pH=7)   -0.064840831

Topological polar surface area  792.27

Aromaticity  0.045454545

Average rotatable bonds  3.272727273

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  29

X logP energy  -3.0045

Hydropathy 



Literature Information


Title  A Scj1p homolog and folding catalysts present in dog pancreas microsomes.

DOI  10.1515/BC.1999.149,

Publication Year  1999

PubMed ID  10595580,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.