General Information
SPKB ID SPKB05429
Signal sequence MHAIAPRLLLLFVLSGLPGTRG
Length 22
Organism Human herpesvirus 2 (strain B4327UR) (HHV-2) (Human herpes simplex virus 2)
UniProt ID P81780,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB05429.cif
Physicochemical Information
Molecular weight 2332.87894
Aliphatic index 146.3636364
Isoelectric point 12.50011018
Charge (pH=7) 2.088886768
Topological polar surface area 849.78
Aromaticity 0.045454545
Average rotatable bonds 3.318181818
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 29
X logP energy -4.63456
Hydropathy
Literature Information
Title Herpes simplex virus type 2 glycoprotein G-negative clinical isolates are generated by single frameshift mutations.
DOI 10.1128/JVI.73.12.9796-9802.1999,
Publication Year 1999
PubMed ID 10559290,
Patent ID NA,