SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05428

Signal sequence   MAAAIPRAASLSPLFPLLFLLSAPQDSSG

Length  29

Organism  Bos taurus (Bovine)

UniProt ID  P81623,

Motif  1..29



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05428.cif

Structure  SPKB05428.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2942.46614

Aliphatic index  114.8275862

Isoelectric point  6.338718596

Charge (pH=7)   -0.001572528

Topological polar surface area  1086.4

Aromaticity  0.068965517

Average rotatable bonds  3.034482759

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  39

X logP energy  -9.72553

Hydropathy 



Literature Information


Title  ERp28, a human endoplasmic-reticulum-lumenal protein, is a member of the protein disulfide isomerase family but lacks a CXXC thioredoxin-box motif.

DOI  10.1046/j.1432-1327.1998.2550570.x,

Publication Year  1998

PubMed ID  9738895,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.