General Information
SPKB ID SPKB05426
Signal sequence MFLLVFLCCLHLVIS
Length 15
Organism Hirudo medicinalis (Medicinal leech)
UniProt ID P81511,
Motif 1..15
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB05426.cif
Physicochemical Information
Molecular weight 1751.27954
Aliphatic index 194.6666667
Isoelectric point 7.253156577
Charge (pH=7) -0.035056042
Topological polar surface area 519.63
Aromaticity 0.133333333
Average rotatable bonds 3.666666667
Number of hydrogen bond donors 20
Number of hydrogen bond acceptors 21
X logP energy 1.8303
Hydropathy 
Literature Information
Title A carboxypeptidase inhibitor from the medical leech Hirudo medicinalis. Isolation, sequence analysis, cDNA cloning, recombinant expression, and characterization.
Publication Year 1998
PubMed ID 9830043,
Patent ID NA,
