SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05422

Signal sequence   MNFTKLFAIVLLAALVLLGQTEA

Length  23

Organism  Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta)

UniProt ID  P81417,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05422.cif

Structure  SPKB05422.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2477.04344

Aliphatic index  161.3043478

Isoelectric point  6.408795646

Charge (pH=7)   -0.000535612

Topological polar surface area  893.48

Aromaticity  0.086956522

Average rotatable bonds  3.565217391

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  31

X logP energy  -3.4556

Hydropathy 



Literature Information


Title  Peptide sequence of an antibiotic cecropin from the vector mosquito, Aedes albopictus.

DOI  10.1006/bbrc.1998.9150,

Publication Year  1998

PubMed ID  9712710,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.