SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05419

Signal sequence   MAALWLQAFSLLVLMMVSWPGSQA

Length  24

Organism  Oreochromis niloticus (Nile tilapia) (Tilapia nilotica)

UniProt ID  P81025,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05419.cif

Structure  SPKB05419.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2651.23804

Aliphatic index  122.0833333

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  902.28

Aromaticity  0.125

Average rotatable bonds  3.416666667

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  33

X logP energy  -3.2337

Hydropathy 



Literature Information


Title  Characterization of the pancreatic hormones from the Brockmann body of the tilapia: implications for islet xenograft studies.

DOI  10.1016/0742-8413(95)00023-z,

Publication Year  1995

PubMed ID  7656183,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.