SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05417

Signal sequence   MKFSLVATIVLLALAQGSFA

Length  20

Organism  Myoxocephalus octodecemspinosus (Longhorn sculpin) (Cottus octodecemspinosus)

UniProt ID  P80961,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05417.cif

Structure  SPKB05417.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2080.55664

Aliphatic index  146.5

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  746.02

Aromaticity  0.1

Average rotatable bonds  3.4

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -4.1386

Hydropathy 



Literature Information


Title  Amino acid sequence of a new type of antifreeze protein, from the longhorn sculpin Myoxocephalus octodecimspinosis.

DOI  10.1016/s0014-5793(96)01466-4,

Publication Year  1997

PubMed ID  9013849,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.