SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05406

Signal sequence   MFGHTSVSFLLLSIVALGMVATVIC

Length  25

Organism  Conus marmoreus (Marble cone)

UniProt ID  P69770,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05406.cif

Structure  SPKB05406.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2610.22654

Aliphatic index  148

Isoelectric point  7.35902981

Charge (pH=7)   0.026918674

Topological polar surface area  891.55

Aromaticity  0.08

Average rotatable bonds  3.32

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  35

X logP energy  -5.1376

Hydropathy 



Literature Information


Title  Isolation and characterization of three novel Gla-containing Conus marmoreus venom peptides, one with a novel cysteine pattern.

DOI  10.1016/j.bbrc.2004.05.088,

Publication Year  2004

PubMed ID  15194478,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.