SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05401

Signal sequence   MYKLTVFLMFIAFVIIAEA

Length  19

Organism  Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)

UniProt ID  P67788,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05401.cif

Structure  SPKB05401.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2220.79954

Aliphatic index  148.9473684

Isoelectric point  6.402001171

Charge (pH=7)   -0.001386026

Topological polar surface area  690.9

Aromaticity  0.210526316

Average rotatable bonds  3.736842105

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  26

X logP energy  2.2841

Hydropathy 



Literature Information


Title  Amino acid sequence of Manduca sexta adipokinetic hormone elucidated by combined fast atom bombardment (FAB)/tandem mass spectrometry.

DOI  10.1016/0006-291x(85)91880-7,

Publication Year  1985

PubMed ID  4074373,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.