SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05398

Signal sequence   MKTLLLTLLVVTIVCLDLGYT

Length  21

Organism  Naja kaouthia (Monocled cobra) (Naja siamensis)

UniProt ID  P60771,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05398.cif

Structure  SPKB05398.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2322.93064

Aliphatic index  190

Isoelectric point  6.157533513

Charge (pH=7)   -0.06468938

Topological polar surface area  809.79

Aromaticity  0.047619048

Average rotatable bonds  3.619047619

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  31

X logP energy  -2.1794

Hydropathy 



Literature Information


Title  A novel short neurotoxin, cobrotoxin c, from monocellate cobra (Naja kaouthia) venom: isolation and purification, primary and secondary structure determination, and tertiary structure modeling.

DOI  10.1016/s1532-0456(02)00049-2,

Publication Year  2002

PubMed ID  12039691,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.