SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05388

Signal sequence   MVTRVGSGFSVQRVWLLLVIVVVLCGSVTQQ

Length  31

Organism  Homarus americanus (American lobster)

UniProt ID  P55320,

Motif  1..31



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05388.cif

Structure  SPKB05388.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3375.09444

Aliphatic index  147.0967742

Isoelectric point  10.52640717

Charge (pH=7)   1.936002961

Topological polar surface area  1306.33

Aromaticity  0.064516129

Average rotatable bonds  3.548387097

Number of hydrogen bond donors  48

Number of hydrogen bond acceptors  44

X logP energy  -10.31786

Hydropathy 



Literature Information


Title  Primary structure of two isoforms of the vitellogenesis inhibiting hormone from the lobster Homarus americanus.

DOI  10.1016/0143-4179(91)90036-i,

Publication Year  1991

PubMed ID  1791922,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.