SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05386

Signal sequence   MLLPRRGLRTLPSLCLYILVLVWVVAC

Length  27

Organism  Oryctolagus cuniculus (Rabbit)

UniProt ID  P55057,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05386.cif

Structure  SPKB05386.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3098.94954

Aliphatic index  176.6666667

Isoelectric point  9.593644853

Charge (pH=7)   2.873174519

Topological polar surface area  1064.52

Aromaticity  0.074074074

Average rotatable bonds  3.555555556

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  37

X logP energy  -1.84639

Hydropathy 



Literature Information


Title  Identification, characterization, cloning, and expression of apolipoprotein C-IV, a novel sialoglycoprotein of rabbit plasma lipoproteins.

DOI  10.1074/jbc.271.3.1776,

Publication Year  1996

PubMed ID  8576182,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.