SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05384

Signal sequence   MQFSIIAISFLASLAMASPAKR

Length  22

Organism  Cryphonectria parasitica (Chestnut blight fungus) (Endothia parasitica)

UniProt ID  P52753,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05384.cif

Structure  SPKB05384.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2353.86644

Aliphatic index  111.3636364

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  877.56

Aromaticity  0.090909091

Average rotatable bonds  3.5

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  32

X logP energy  -6.96613

Hydropathy 



Literature Information


Title  Virus-associated down-regulation of the gene encoding cryparin, an abundant cell-surface protein from the chestnut blight fungus, Cryphonectria parasitica.

DOI  10.1016/0378-1119(94)90523-1,

Publication Year  1994

PubMed ID  8112589,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.