SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05383

Signal sequence   MAPQTSNLWILLLLVVVMMMSQGCC

Length  25

Organism  Sparus aurata (Gilthead sea bream)

UniProt ID  P51919,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05383.cif

Structure  SPKB05383.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2782.50474

Aliphatic index  132.4

Isoelectric point  5.826007312

Charge (pH=7)   -0.125965132

Topological polar surface area  958.68

Aromaticity  0.04

Average rotatable bonds  3.6

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  38

X logP energy  -5.1966

Hydropathy 



Literature Information


Title  Three forms of gonadotropin-releasing hormone characterized from brains of one species.

DOI  10.1073/pnas.91.25.12081,

Publication Year  1994

PubMed ID  7991588,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.