SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05382

Signal sequence   MKRLILPFLSVGLLLGTTAHA

Length  21

Organism  Coxiella burnetii (strain RSA 493 / Nine Mile phase I)

UniProt ID  P51752,

Motif  1..21



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05382.cif

Structure  SPKB05382.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2251.80204

Aliphatic index  153.3333333

Isoelectric point  11.65178972

Charge (pH=7)   2.088595045

Topological polar surface area  813.82

Aromaticity  0.047619048

Average rotatable bonds  3.476190476

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  29

X logP energy  -4.01043

Hydropathy 



Literature Information


Title  Molecular cloning of a Coxiella burnetii gene encoding a macrophage infectivity potentiator (Mip) analogue.

DOI  10.1099/13500872-141-11-2861,

Publication Year  1995

PubMed ID  8535514,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.