SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05381

Signal sequence   MRNARSTLITTAGMAFAVLGLLFALAGPSAGRAEA

Length  35

Organism  Streptomyces lividans

UniProt ID  P51529,

Motif  1..35



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05381.cif

Structure  SPKB05381.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3507.12964

Aliphatic index  100.8571429

Isoelectric point  12.19913393

Charge (pH=7)   1.999749488

Topological polar surface area  1411.17

Aromaticity  0.057142857

Average rotatable bonds  3.228571429

Number of hydrogen bond donors  51

Number of hydrogen bond acceptors  48

X logP energy  -15.32639

Hydropathy 



Literature Information


Title  Beta-mannanase of Streptomyces lividans 66: cloning and DNA sequence of the manA gene and characterization of the enzyme.

DOI  10.1042/bj2900857,

Publication Year  1993

PubMed ID  8457214,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.