SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05380

Signal sequence   MMKTLVVVLSLSLTILSFGGAHA

Length  23

Organism  Prunus avium (Cherry) (Cerasus avium)

UniProt ID  P50694,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05380.cif

Structure  SPKB05380.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2388.95264

Aliphatic index  148.2608696

Isoelectric point  9.702001779

Charge (pH=7)   1.088598356

Topological polar surface area  859.37

Aromaticity  0.043478261

Average rotatable bonds  3.434782609

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  33

X logP energy  -5.8067

Hydropathy 



Literature Information


Title  Biochemical characterization of Pru a 2, a 23-kD thaumatin-like protein representing a potential major allergen in cherry (Prunus avium).

DOI  10.1159/000023920,

Publication Year  1998

PubMed ID  9623505,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.