General Information
SPKB ID SPKB05379
Signal sequence MSKLFFVVFLCLIISVFA
Length 18
Organism Latrodectus tredecimguttatus (Mediterranean black widow spider) (Latrodectus mactans tredecimguttatus)
UniProt ID P49125,
Motif 1..18
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB05379.cif
Physicochemical Information
Molecular weight 2077.65714
Aliphatic index 162.2222222
Isoelectric point 8.545189979
Charge (pH=7) 0.93571455
Topological polar surface area 624.5
Aromaticity 0.222222222
Average rotatable bonds 3.666666667
Number of hydrogen bond donors 23
Number of hydrogen bond acceptors 24
X logP energy 1.6256
Hydropathy
Literature Information
Title Cloning and activity of a novel alpha-latrotoxin from red-back spider venom.
DOI 10.1016/j.bcp.2011.09.024,
Publication Year 2012
PubMed ID 22001442,
Patent ID NA,