SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05371

Signal sequence   MKVFSAVLIILFVCSMIIGINA

Length  22

Organism  Androctonus australis (Sahara scorpion)

UniProt ID  P45696,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05371.cif

Structure  SPKB05371.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2383.04984

Aliphatic index  172.7272727

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  783.99

Aromaticity  0.090909091

Average rotatable bonds  3.590909091

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  30

X logP energy  -1.5486

Hydropathy 



Literature Information


Title  The kaliotoxin family enlarged. Purification, characterization, and precursor nucleotide sequence of KTX2 from Androctonus australis venom.

DOI  NA,

Publication Year  1994

PubMed ID  7806508,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.