SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05363

Signal sequence   MVSVCRLLLVAALLLCLQAQLSFS

Length  24

Organism  Clarias gariepinus (North African catfish) (Silurus gariepinus)

UniProt ID  P43306,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05363.cif

Structure  SPKB05363.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2592.25494

Aliphatic index  178.75

Isoelectric point  8.231408964

Charge (pH=7)   0.874031556

Topological polar surface area  941.39

Aromaticity  0.041666667

Average rotatable bonds  3.583333333

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  34

X logP energy  -5.42823

Hydropathy 



Literature Information


Title  Two gonadotropin-releasing hormones from African catfish (Clarias gariepinus).

DOI  10.1016/s0006-291x(05)81468-8,

Publication Year  1992

PubMed ID  1520292,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.