SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05339

Signal sequence   MAVRLWVVALALAALFIVDREVPVSA

Length  26

Organism  Sus scrofa (Pig)

UniProt ID  P37109,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05339.cif

Structure  SPKB05339.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2810.43704

Aliphatic index  165

Isoelectric point  6.495679141

Charge (pH=7)   0.000199284

Topological polar surface area  1016.45

Aromaticity  0.076923077

Average rotatable bonds  3.346153846

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  33

X logP energy  -3.11146

Hydropathy 



Literature Information


Title  Isolation and characterization of a 60-residue intestinal peptide structurally related to the pancreatic secretory type of trypsin inhibitor: influence on insulin secretion.

DOI  10.1073/pnas.86.21.8590,

Publication Year  1989

PubMed ID  2573065,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.