General Information
SPKB ID SPKB05338
Signal sequence MKAWIFFLVCLAGRALA
Length 17
Organism Oryctolagus cuniculus (Rabbit)
UniProt ID P36233,
Motif 1..17
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB05338.cif
Physicochemical Information
Molecular weight 1910.41194
Aliphatic index 132.3529412
Isoelectric point 9.833242293
Charge (pH=7) 1.935711238
Topological polar surface area 632.63
Aromaticity 0.176470588
Average rotatable bonds 3.529411765
Number of hydrogen bond donors 24
Number of hydrogen bond acceptors 22
X logP energy -0.00893
Hydropathy
Literature Information
Title Osteonectin/SPARC is a product of articular chondrocytes/cartilage and is regulated by cytokines and growth factors.
DOI 10.1016/0167-4889(94)90209-7,
Publication Year 1994
PubMed ID 8130279,
Patent ID NA,