SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05316

Signal sequence   MGLNRFMRAMMVVFITANCITINPDIIFA

Length  29

Organism  Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)

UniProt ID  P33379,

Motif  1..29



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05316.cif

Structure  SPKB05316.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3304.06604

Aliphatic index  111.0344828

Isoelectric point  8.54983383

Charge (pH=7)   0.936449445

Topological polar surface area  1200.16

Aromaticity  0.103448276

Average rotatable bonds  3.689655172

Number of hydrogen bond donors  42

Number of hydrogen bond acceptors  43

X logP energy  -7.18206

Hydropathy 



Literature Information


Title  A novel bacterial virulence gene in Listeria monocytogenes required for host cell microfilament interaction with homology to the proline-rich region of vinculin.

DOI  10.1002/j.1460-2075.1992.tb05252.x,

Publication Year  1992

PubMed ID  1582425,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.