SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05312

Signal sequence   MLKNKILATTLSVSLLAPLANPLLENAKA

Length  29

Organism  Staphylococcus aureus

UniProt ID  P31716,

Motif  1..29



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05312.cif

Structure  SPKB05312.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3048.71824

Aliphatic index  148.2758621

Isoelectric point  10.506919

Charge (pH=7)   1.998874321

Topological polar surface area  1186.09

Aromaticity  0

Average rotatable bonds  3.517241379

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  42

X logP energy  -9.4672

Hydropathy 



Literature Information


Title  Nucleotide sequence of leukocidin S-component gene (lukS) from methicillin resistant Staphylococcus aureus.

DOI  10.1016/s0006-291x(05)81392-0,

Publication Year  1991

PubMed ID  1958181,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.