SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05311

Signal sequence   MKMNKLVKSSVATSMALLLLSGTAN

Length  25

Organism  Staphylococcus aureus

UniProt ID  P31715,

Motif  1..25



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05311.cif

Structure  SPKB05311.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2609.19644

Aliphatic index  113.2

Isoelectric point  11.10307074

Charge (pH=7)   2.997099198

Topological polar surface area  1047.34

Aromaticity  0

Average rotatable bonds  3.68

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  40

X logP energy  -11.605

Hydropathy 



Literature Information


Title  Molecular cloning and nucleotide sequence of leukocidin F-component gene (lukF) from methicillin resistant Staphylococcus aureus.

DOI  10.1016/0006-291x(92)90637-z,

Publication Year  1992

PubMed ID  1575738,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.