SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05309

Signal sequence   MKLLILTICALHVNQMMA

Length  18

Organism  Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)

UniProt ID  P31420,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05309.cif

Structure  SPKB05309.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2043.63324

Aliphatic index  157.2222222

Isoelectric point  8.552755748

Charge (pH=7)   1.026623641

Topological polar surface area  719.13

Aromaticity  0

Average rotatable bonds  3.888888889

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  28

X logP energy  -2.5821

Hydropathy 



Literature Information


Title  Purification and properties of an ommochrome-binding protein from the hemolymph of the tobacco hornworm, Manduca sexta.

DOI  NA,

Publication Year  1991

PubMed ID  1939173,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.