SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05301

Signal sequence   MSTWWLVVVAAAAAAGLVRAEDRYHPERLAAGEASAATR

Length  39

Organism  Bombyx mori (Silk moth)

UniProt ID  P29523,

Motif  1..39



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05301.cif

Structure  SPKB05301.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4125.67774

Aliphatic index  90.51282051

Isoelectric point  7.545909622

Charge (pH=7)   0.093801583

Topological polar surface area  1718.54

Aromaticity  0.076923077

Average rotatable bonds  3.282051282

Number of hydrogen bond donors  63

Number of hydrogen bond acceptors  55

X logP energy  -16.42562

Hydropathy 



Literature Information


Title  Cloning and sequence analysis of membrane-bound alkaline phosphatase cDNA of the silkworm, Bombyx mori.

DOI  10.1016/0167-4781(91)90229-f,

Publication Year  1991

PubMed ID  1756175,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.