SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05297

Signal sequence   MRSIKAASLTPLLAALFTTLSSTLALPSSVWEHQL

Length  35

Organism  Candida tsukubaensis (Yeast) (Pseudozyma tsukubaensis)

UniProt ID  P29064,

Motif  1..35



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05297.cif

Structure  SPKB05297.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3755.43074

Aliphatic index  122.8571429

Isoelectric point  9.697026921

Charge (pH=7)   1.090370168

Topological polar surface area  1450.22

Aromaticity  0.057142857

Average rotatable bonds  3.4

Number of hydrogen bond donors  52

Number of hydrogen bond acceptors  52

X logP energy  -13.25053

Hydropathy 



Literature Information


Title  Primary structure and processing of the Candida tsukubaensis alpha-glucosidase. Homology with the rabbit intestinal sucrase-isomaltase complex and human lysosomal alpha-glucosidase.

DOI  10.1111/j.1432-1033.1991.tb16420.x,

Publication Year  1991

PubMed ID  1761061,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.