SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05291

Signal sequence   MRKFTLLMLLLIVISMSGIAGA

Length  22

Organism  Methanothermus fervidus (strain ATCC 43054 / DSM 2088 / JCM 10308 / V24 S)

UniProt ID  P27373,

Motif  1..22



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell wall

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05291.cif

Structure  SPKB05291.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2379.06194

Aliphatic index  164.0909091

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  823.03

Aromaticity  0.045454545

Average rotatable bonds  3.727272727

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  31

X logP energy  -2.83383

Hydropathy 



Literature Information


Title  Analysis and nucleotide sequence of the genes encoding the surface-layer glycoproteins of the hyperthermophilic methanogens Methanothermus fervidus and Methanothermus sociabilis.

DOI  10.1111/j.1432-1033.1991.tb16102.x,

Publication Year  1991

PubMed ID  1712296,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.