SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05281

Signal sequence   MAGVWKVLVVLVGLAVVACA

Length  20

Organism  Oryctolagus cuniculus (Rabbit)

UniProt ID  P26202,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05281.cif

Structure  SPKB05281.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1998.55934

Aliphatic index  180

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  658.03

Aromaticity  0.05

Average rotatable bonds  3.1

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  24

X logP energy  -0.7819

Hydropathy 



Literature Information


Title  Isolation of two isoforms of a novel 15-kDa protein from rabbit polymorphonuclear leukocytes that modulate the antibacterial actions of other leukocyte proteins.

DOI  NA,

Publication Year  1990

PubMed ID  2203792,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.