SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05276

Signal sequence   MVGVRLVFTNAFVVTVLLTLLLDVVVKPAEG

Length  31

Organism  Lymnaea stagnalis (Great pond snail) (Helix stagnalis)

UniProt ID  P25289,

Motif  1..31



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05276.cif

Structure  SPKB05276.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3314.07374

Aliphatic index  166.1290323

Isoelectric point  6.494323083

Charge (pH=7)   -0.0000924

Topological polar surface area  1193.83

Aromaticity  0.064516129

Average rotatable bonds  3.419354839

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  41

X logP energy  -5.08023

Hydropathy 



Literature Information


Title  Purification and sequencing of molluscan insulin-related peptide II from the neuroendocrine light green cells in Lymnaea stagnalis.

DOI  10.1210/endo.130.6.1350761,

Publication Year  1992

PubMed ID  1350761,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.