SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05274

Signal sequence   MRLHHLLLALLFLVLSAWSGFTQGVG

Length  26

Organism  Bos taurus (Bovine)

UniProt ID  P25068,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05274.cif

Structure  SPKB05274.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2880.48984

Aliphatic index  150

Isoelectric point  10.55350111

Charge (pH=7)   1.17979917

Topological polar surface area  1029.65

Aromaticity  0.115384615

Average rotatable bonds  3.538461538

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  35

X logP energy  -4.07863

Hydropathy 



Literature Information


Title  Tracheal antimicrobial peptide, a cysteine-rich peptide from mammalian tracheal mucosa: peptide isolation and cloning of a cDNA.

DOI  10.1073/pnas.88.9.3952,

Publication Year  1991

PubMed ID  2023943,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.