SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05273

Signal sequence   MLPLCLVAALLLSASGPRPSLG

Length  22

Organism  Sus scrofa (Pig)

UniProt ID  P24854,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05273.cif

Structure  SPKB05273.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2179.70744

Aliphatic index  150.9090909

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  770.64

Aromaticity  0

Average rotatable bonds  3

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  29

X logP energy  -5.67803

Hydropathy 



Literature Information


Title  Identification and NH2-terminal amino acid sequence of three insulin-like growth factor-binding proteins in porcine serum.

DOI  10.1016/0006-291x(91)92056-p,

Publication Year  1991

PubMed ID  1722398,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.