SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05272

Signal sequence   MIRFLVFSLLILTLFLTAPAV

Length  21

Organism  Trichosanthes kirilowii (Chinese snake gourd) (Chinese cucumber)

UniProt ID  P24478,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05272.cif

Structure  SPKB05272.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2379.02824

Aliphatic index  185.7142857

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  759.12

Aromaticity  0.142857143

Average rotatable bonds  3.523809524

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  27

X logP energy  0.81947

Hydropathy 



Literature Information


Title  Amino acid sequences and ribosome-inactivating activities of karasurin-B and karasurin-C.

DOI  10.1248/bpb.19.1485,

Publication Year  1996

PubMed ID  8951169,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.