SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05271

Signal sequence   MKLLLLLVISASMLLECLVNA

Length  21

Organism  Hottentotta judaicus (Black scorpion) (Buthotus judaicus)

UniProt ID  P24336,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05271.cif

Structure  SPKB05271.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2287.94644

Aliphatic index  204.2857143

Isoelectric point  6.231833229

Charge (pH=7)   -0.062510328

Topological polar surface area  792.19

Aromaticity  0

Average rotatable bonds  3.761904762

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  30

X logP energy  -1.8492

Hydropathy 



Literature Information


Title  Functional duality and structural uniqueness of depressant insect-selective neurotoxins.

DOI  10.1021/bi00233a025,

Publication Year  1991

PubMed ID  2029523,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.