SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05270

Signal sequence   MKILYLLFAFLFLAFLSEPGNA

Length  22

Organism  Crotalus adamanteus (Eastern diamondback rattlesnake)

UniProt ID  P24330,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05270.cif

Structure  SPKB05270.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2519.08264

Aliphatic index  137.7272727

Isoelectric point  6.402001171

Charge (pH=7)   -0.001386026

Topological polar surface area  812.5

Aromaticity  0.227272727

Average rotatable bonds  3.590909091

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  29

X logP energy  0.6328

Hydropathy 



Literature Information


Title  Amino acid sequence of a myotoxin from venom of the eastern diamondback rattlesnake (Crotalus adamanteus).

DOI  10.1016/0041-0101(91)90020-r,

Publication Year  1991

PubMed ID  1862521,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.