SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB05268

Signal sequence   MKNKLLFKIFLSLSLALSVYSINDKIIEVSNTSLA

Length  35

Organism  Staphylococcus aureus

UniProt ID  P24121,

Motif  1..35



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB05268.cif

Structure  SPKB05268.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3914.69944

Aliphatic index  144.8571429

Isoelectric point  10.02740516

Charge (pH=7)   1.998175357

Topological polar surface area  1522.51

Aromaticity  0.085714286

Average rotatable bonds  3.885714286

Number of hydrogen bond donors  53

Number of hydrogen bond acceptors  54

X logP energy  -11.2565

Hydropathy 



Literature Information


Title  Molecular cloning and sequencing of the epidermal cell differentiation inhibitor gene from Staphylococcus aureus.

DOI  10.1016/0006-291x(91)91438-i,

Publication Year  1991

PubMed ID  1993048,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.